产品货号：
Z20147
中文名称：
MAX抗体
英文名称：
Anti-MAX Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MAX Antibody |
| 指标别名 | bHLHd4;bHLHd5;bHLHd6;bHLHd7;bHLHd8;MAX;MYC associated factor X;orf1;Protein max |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,ICC/IF,FCM(Intracellular),ELISA |
| 基因名称 | MAX |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MAX recombinant protein (Position:A30-R106). |
| 实际分子量 | 19～21KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MAX(Max protein),also called Myc-associated factor x,is the most conserved dimerization component of the MYC-MAX-MXD1 network of basic helix-loop-helix leucine zipper (bHLHZ) transcription factors that regulate cell proliferation,differentiation,and apoptosis.The conservation of the MAX sequence is particularly high in the bHLHZ domain,which is involved in protein-protein interactions and DNA binding.The MAX gene is located on chromosome 14q23 by fluorescence in situ chromosomal hybridization.Both quasisymmetric heterodimers resemble the symmetric MAX homodimer,albeit with marked structural differences in the coiled-coil leucine zipper regions that explain preferential homo- and heteromeric dimerization of these 3 evolutionarily related DNA-binding proteins.MAX acts as a classic tumor suppressor gene.Normal lymphocytes from patients showed absence of methylation of the MAX promoter and biallelic expression of MAX,which ruled out an imprinting-mediated effect on MAX expression.The ability of these cells to divide,differentiate,and apoptose in the absence of Max demonstrated for the first time that these processes can occur via Max- and possibly Myc-independent mechanisms. |
| Uniprot ID | P61244 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 |
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